銆愮鑳朵箟涔炽€戣繃缁嗚優褰㈢姸鍒ゆ柇涔崇檶鐨勬柟寮忥紝浣犺杩囧悧锛焈闆鸡瀹樼綉-乐乐捕鱼2

闆鸡瀹炰笟
  • 褰撳墠浣嶇疆: > 鍋ュ悍鎸囧崡 >
  • 銆愮鑳朵箟涔炽€戣繃缁嗚優褰㈢姸鍒ゆ柇涔崇檶鐨勬柟寮忥紝浣犺杩囧悧锛?/h2>

    鍙戝竷浜?2017-02-28 09:56鏉ユ簮:闆鸡涔変钩

          闆鸡锛氳繎鏉ワ紝鑻卞浗浼︽暒鐧岀棁鐮旂┒鎵€(institute of cancer research in london锛孖cr)鐨勭瀛﹀浠垱寤轰簡涓€涓?ldquo;鍦板浘”锛屾妸涔宠吅鐧岀粏鑳炵殑褰㈢姸涓庡熀鍥犺仈绯昏捣鏉ワ紝浣垮緱鍖荤敓鍙互閫氳繃缁嗚優褰㈢姸鍒ゆ柇鐥呮儏锛屽苟鎻愬嚭鏇存湁閽堝鎬х殑娌荤枟鏂规銆?/span>

     

          绉戝鏋滅劧鍏呮弧浜嗗鎬濆鎯冲晩銆?/span>

     

     

          icr鐨勯甯瀛﹀karen vousden鏁欐巿璇达細”鎴戜滑宸茬粡鍒涘缓鐨勭粏鑳炲舰鐘跺強鍏跺鍩哄洜娲绘€у奖鍝嶇殑缃戠粶鍥撅紝鎻愪緵浜嗘柊褰㈠紡鐨勭檶鐥囨不鐤楅噸瑕佹寚鏍囷紝浠ュ強浣跨幇鏈夋不鐤楁墜娈垫洿鏈夋晥鐨勬柟娉曘€?rdquo;

     

          绠€鍗曠殑璇村氨鏄紝icr鍙戠幇鐧岀粏鑳炰細鏀瑰彉褰㈢姸锛屼互鍝嶅簲鍜屼繚鎶よ嚜宸卞厤鍙楀懆鍥寸幆澧冪殑褰卞搷銆傛瘮濡傦紝鍦ㄨ偪鐦や腑锛岀粏鑳炰細琚繛缁湴鎺ㄦ媺銆佷几灞曞拰鎸ゅ帇銆傝繖浜涘彉鍖栵紝瀹為檯涓婁笌鎮h€呯殑涓村簥鐤剧梾缁撴灉鐩稿叧鑱斻€?/span>

     

          浠栦滑杩樺彂鐜帮紝涓€涓绉颁负nf-kappab鐨勮泲鐧借川鍦ㄨ繖绉嶅舰鐘?鍩哄洜缃戠粶涓彂鎸ヤ腑蹇冧綔鐢紝骞朵笖鍙互椹卞姩鐧岀粏鑳炵殑鐢熼暱鍜屾墿鏁c€傝繖绉嶅弽搴斾笌鎮h€呯殑鑲跨槫鍒嗙骇鐩稿叧锛屽彲鐢ㄤ簬棰勬祴鐢熷瓨銆?/span>

     

          涔熷氨鏄锛孖cr鎵惧埌浜?a href='http://www.xuelun.net' target='_blank'>涔宠吅鐧?/u>鐨勫瑙傜壒寰佸拰琛屼负涔嬮棿鐨勮仈绯伙紝浠ュ強瀹冪殑鍩哄洜缁勬垚锛屽彲浠ュ府鍔╃爺绌朵汉鍛樺紑鍙戞洿璇︾粏鐨勭柧鐥呮不鐤楁柟妗堛€?/span>

     

          karen vousden璇达紝杩欓」鐮旂┒寰堝揩灏嗕娇鍖荤敓鑳藉渚濇嵁鍗曠嫭鐨勭粏鑳炲瑙傜壒寰侊紝鑾风煡鐧岀棁鐨勪镜琚€у拰瀹冨彲鑳戒紶鎾殑閫熷害锛屽府鍔╁尰鐢熷喅瀹氫粈涔堟槸閽堝鎮h€呯殑娌荤枟鏂瑰紡銆?/span>

     

          杩欓」鐮旂┒缁撴灉锛屽彂琛ㄥ湪绉戠爺鏉傚織銆奊enome research銆嬩笂銆?/span>

     

          鍦ㄨ繖椤圭爺绌朵腑锛岀瀛﹀浠娇鐢ㄤ簡鍖呭惈18涓钩鑵虹檶缁嗚優绯讳腑307643涓粏鑳炵殑缁嗚優褰㈢姸娴嬮噺鐨勬暟鎹泦锛屼粩缁嗗湴瑙傚療浜嗚繖30澶氫竾涓钩鑵虹檶缁嗚優鐨勬暟鐧句竾涓垚鍍忔壂鎻忎骇鐢熺殑缁嗚優褰㈢姸锛屽悓鏃惰繕鐮旂┒浜嗘弿杩拌法鐩稿悓缁嗚優绯荤殑28376涓熀鍥犵殑琛ㄨ揪鏁版嵁闆嗐€?/span>

     

          icr鏄笘鐣屼笂鍏峰奖鍝嶅姏鐨勭檶鐥囩爺绌剁粍缁囦箣涓€锛屽畠鏇剧粡鎻愪緵浜嗙涓€涓护浜轰俊鏈嶇殑璇佹嵁琛ㄦ槑dna鎹熶激鏄檶鐥囩殑鍩烘湰鍘熷洜锛屼负鐜板湪鏅亶鎺ュ彈鐨勭檶鐥囨槸閬椾紶鎬х柧鐥呯殑璁炬兂濂犲畾浜嗗熀纭€銆?/span>

     

          闅忕潃绉戞妧鐨勫彂灞曪紝涔宠吅鐧岀殑娌荤枟宸蹭粠鍘熸湁鐨勭粡楠屾€ф不鐤楄繃娓″埌浜嗕釜浣撳寲鐨?ldquo;绮惧噯娌荤枟”銆備竴鐩翠互鏉ワ紝绐佸彉鏁版嵁搴撶殑缂轰箯涓€鐩村埗绾︾潃鍩哄洜妫€娴嬬殑鍙戝睍銆傝€屾渶涓轰钩鑵虹檶鎮h€呯啛鐭ョ殑鏄疊rca鍩哄洜鐨勭獊鍙樸€傜幇鏈夌爺绌跺凡鏄庣‘璇佸疄锛孊rca1/2鍩哄洜鐨勮儦绯荤獊鍙樹笌閬椾紶鎬т钩鑵虹檶鐨勫彂鐢熷瘑鍒囩浉鍏炽€傞仐浼犳€т钩鑵虹檶绾﹀崰鎵€鏈変钩鑵虹檶5%~10%锛屽叾鍙戠梾骞撮緞鐩稿骞磋交锛?0宀佷互涓嬬殑骞磋交涔宠吅鐧屾偅鑰呬腑绾?5%-35%鏈変钩鑵虹檶鏄撴劅鍩哄洜鐨勭獊鍙樸€傛洿閲嶈鐨勬槸锛屾惡甯rca1/2鍩哄洜绐佸彉鐨勫濂筹紝鍏朵竴鐢熶腑鎮d钩鑵虹檶銆佸嵉宸㈢檶鐨勫嵄闄╀細闅忓勾榫勫闀胯€屽楂橈紝brca1/2绐佸彉鎼哄甫鑰呭埌80宀佹椂鍙戠敓涔宠吅鐧岀殑棰勬祴绱н椋庨櫓鍧囪秴杩?0%銆?/span>
     

          “骞插緱婕備寒锛佸紩鍙戜钩鑵虹檶鐨勫熀鍥犵獊鍙橀兘鎵惧埌浜?rdquo;鎺ㄩ€佷腑鏇炬彁鍒帮紝鍖诲鐣屽凡鍦ㄤ粖骞?鏈堝彂鐜颁簡鍙兘寮曞彂涔宠吅鐧岀殑鍑犱箮鍏ㄩ儴鐨勫熀鍥犵獊鍙橈紝鏁伴噺澶氳揪93涓€傚叾涓紝鏈?1涓钩鑵虹檶鑷寸檶鎴栨姂鐧屽熀鍥犵獊鍙橀鐜囪緝楂橈細brca1锛汢rca2锛汣hek2锛汸alb2锛汢rip1锛汿p53锛汸ten锛汼tk11锛汣dh1锛汚tm锛汢ard1锛汳lh1锛汳re11a锛汳sh2锛汳sh6锛汳utyh锛汵bn锛汸ns1锛汸ms2锛汻ad51c锛汻ad51c

     

          閫氳繃瀵硅偪鐦ょ殑鍩哄洜妫€娴嬶紝婊¤冻鎮h€呬釜浣撳寲闇€姹傜殑鏃╂湡骞查鍜屾不鐤楋紝宸叉垚涓虹鐮斾汉鍛樺拰涓村簥鍖荤敓鐨勫叡鍚屾湡璁搞€?/span>

     

          涓嶈繃锛屼钩鑵虹檶鍦ㄥ叏鐞冨垎甯冩湁鐫€宸ㄥぇ鐨勫樊寮傦紝鑰屼腑鍥藉コ鎬у彂鐥呬汉缇ゅ湪閬椾紶銆佺幆澧冨拰鐢熸椿鏂瑰紡绛夋柟闈笌娆х編涔宠吅鐧岄珮鍙戝湴鍖轰篃鏈夋樉钁楃殑宸紓銆?/span>

     

          杩欎篃鎻愮ず鎴戜滑鍏虫敞涔宠吅鐧屽彲鑳芥洿瑕佸叧娉ㄥ奖鍝嶄腑鍥藉コ鎬х焦鎮d钩鑵虹檶鐨勫洜绱犮€?/span>

     

          姣斿鍦ㄧ敓鑲插勾榫勩€侀ギ椋熶範鎯€佽繍鍔ㄤ笌浣撳瀷锛屼互鍙婅鍔ㄥ惛鐑熻繖鍑犱釜鍥犵礌鏂归潰锛屼腑鍥藉コ鎬т笌澶栧浗杩樻槸瀛樺湪涓€瀹氱殑宸埆銆?/span>

     

          鍘诲勾锛屾湁娑堟伅璇村浗鍐呯殑涔宠吅鐧屾槗鎰熷熀鍥犲簱瑕佸湪涓婃捣钀藉湴銆?/span>

     

          浠庢牴鏈笂鐨勫熀鍥犳娴嬪叆鎵嬶紝鏄钩鑵虹檶绮惧噯鍖荤枟鐨勬柟鍚戜箣涓€锛屽皢鍏嬫湇鐩墠鏅亶閲囩敤鍥藉涔宠吅鐧屾槗鎰熷熀鍥犳暟鎹簱鏉ヨ瘎浼颁腑鍥戒汉鎮g梾椋庨櫓鏃舵墍甯︽潵鐨勫亸宸瓑闂锛屽悓鏃朵负涓村簥鎻愪緵蹇嵎鐨勬暟鎹拷韪拰鏁版嵁鍒嗘瀽銆?br />
          鍐呭鏉ヨ嚜锛氬井淇″叕浼楀彿锛歴hxljkw (闆鸡灞?锛屾兂鑾峰緱鏇村瀹炵敤骞茶揣锛岃鍏虫敞闆鸡纭呰兌瀹樼綉锛侊紒

     

    鏍囩(tag):
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    ------鍒嗛殧绾?---------------------------